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Hey – this seems like a connection issue between your Ledger and your Mac. Try the troubleshooting steps mentioned here to see if that helps.
https://support.ledger.com/hc/en-us/articles/115005165269-Fix-USB-connection-issues-with-Ledger-Live?support=true
Also Make sure all applications and browser extensions are fully closed when attempting to connect. This includes third party wallets (Metamask, Daedalus, MyEtherWallet) or any other application that could interfere with the connection between Ledger Live and your Ledger device.
Try doing a simple restart of your computer. This might be a simple troubleshooting step but can sometimes be the solution to connecting.
Ensure you’re using the USB cable that came with your Ledger device. Some USB cables don’t contain the pins necessary for data communication, and will successfully power your Ledger but won’t allow communication. If you do not have the Ledger USB cable anymore, make sure the cable you use is capable of data transfer.
Turn off any anti-virus, firewall and VPN software on your computer. Try again to access My Ledger or perform the genuine check.
If your Mac has an Intel processor, follow Apple’s official instructions to reset the NVRAM.
If the issue persists then reach out to our support team at https://support.ledger.com/hc/en-us via Contact Us button in the bottom right.